Mariana Oncology Appoints Karen Smith, M.D., Ph.D., as Independent Board Director
Mariana Oncology Appoints Karen Smith, M.D., Ph.D., as Independent Board Director

News & Media

Follow us on our journey as we harness the power of radiopharmaceutical technology to take on cancer’s toughest tumors. This journey has brought us to a new name: We are now Mariana Oncology

Check back here for the latest on Mariana Oncology.

Mariana Oncology Appoints Karen Smith, M.D., Ph.D., as Independent Board Director

CAMBRIDGE, Mass., March 8, 2022 — Mariana Oncology, Inc. (“Mariana Oncology”), a biotechnology company focused on developing innovative radiopharmaceutical therapies for oncological diseases, announced today that it has appointed Karen Smith, M.D., Ph.D., M.B.A., L.L.M., to its Board of Directors.

“It is with much excitement that we welcome Karen to our Board of Directors to provide additional diversity of thought and development experience,” said Simon Read, Mariana Oncology’s CEO and founder. “Karen’s depth of knowledge in oncology drug development, experience on platform and asset-focused company boards, and background spanning medicine, law, and business, will serve us well as we advance our first precision radiopharmaceuticals into the clinic.”

“With a team of seasoned experts across its core capabilities and a mission to deliver an oncology drug profile that has not yet been achieved with existing modalities, Mariana Oncology is uniquely poised to usher in a new era for precision radiopharmaceuticals,” said Dr. Smith. “Together we’ll build and advance a pipeline of radiopharmaceuticals designed to maximize potency, selectivity, and stability, while also achieving rapid systemic clearance. I believe Mariana Oncology’s approach has the potential to result in powerful, novel treatments for patients suffering from solid tumors of high unmet need.”

Dr. Smith has overseen numerous trials and regulatory approvals leading to global product launches of small molecules, biologics and devices across oncology and other therapeutic areas. She is an accomplished executive who has led departments within large pharma (Allergan, Astra-Zeneca, Bristol Myers Squibb), and served as CMO or CEO at notable biotech companies (Jazz, ECI, Novosteo). She currently serves on the boards of Antares Pharma, Sangamo Therapeutics and Emyria Ltd. and has helped guide several successful corporate exits through acquisition (Forward Pharma, Sucampo Pharma, Acceleron Pharma). Dr Smith’s credentials include a B.App.Sc. with a double major in Biotechnology and Haematology; an M.D.; a Ph.D. in oncology molecular genetics; an M.B.A. and a Master of Law (L.L.M.).

About Mariana Oncology
Mariana Oncology Therapeutics is a fully integrated, next-generation radiopharmaceuticals company focused on pioneering a new class of targeted radiopharmaceuticals that are both safe and effective. Mariana Oncology’s radiopharmaceuticals are composed of rationally designed conjugates against carefully selected biological targets, to deliver alpha and beta-emitting radionuclide payloads. Mariana Oncology’s mission is to revolutionize the use of radiomedicines in cancer. Learn more at

Argot Partners
Media: Sarah Sutton
IR: Kevin Murphy